First intraindividual comparison of contrast-enhanced MRI, FET- and DOTATOC- PET in patients with intracranial meningiomas

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First intraindividual comparison of contrast-enhanced MRI, FET- and DOTATOC- PET in patients with intracranial meningiomas

BACKGROUND For irradiation treatment planning of meningiomas the use of PET-scans is well established. The most frequently used tracers are either based on amino acids or the somatostatin receptor ligand DOTATOC. Since up to now no inter-institutionally accepted standard PET-tracer has been defined, the aim of this study was to evaluate the influence of these different types of PET-tracers on t...

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Intraindividual comparison of selective arterial versus venous 68Ga-DOTATOC PET/CT in patients with gastroenteropancreatic neuroendocrine tumors.

PURPOSE Therapy with the somatostatin analogue DOTA-(0)-Phe(1)-Tyr(3)-octreotide (DOTATOC) labeled with a beta-(DOTA-Phe-Tyr-Octreotide) emitter such as 90Y or 177Lu is accepted for the palliative treatment of unresectable neuroendocrine cancer. However, the optimal route of administration has not been determined. Using positron-emission tomography (PET)-labeled 68Ga-DOTATOC, we compared select...

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Simultaneous Perfusion MRI and FET-PET

PET imaging using radiolabelled amino acids tracer can specifically deliver valuable information about tumour extent, malignancy, and tumour recurrence. Perfusion MRI, which measures microcirculatory parameters such as cerebral blood flow (CBF) and cerebral blood volume (CBV), can precisely investigate vascular malformation, and help classify and grade brain tumours. In this study, FETPET and p...

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ژورنال

عنوان ژورنال: Radiation Oncology

سال: 2017

ISSN: 1748-717X

DOI: 10.1186/s13014-017-0913-x